Benedetta Crescenzi
Senior Scientist
Neuilly Plaisance
Profil professionnel
With over 20 years of experience in the pharmaceutical industry, I bring a rare dual expertise in medicinal chemistry and biochemistry/protein sciences. I began my career in a medicinal chemistry group, where I contributed to the discovery of two marketed drugs: raltegravir, an HIV integrase inhibitor, and grazoprevir, an HCV protease inhibitor.
More recently, I joined a protein sciences group, focusing on the production, purification, and characterization of biological targets for drug discovery.
This combined experience—ranging from designing bioactive compounds to mastering biological targets—represents a strong asset for translational research and cross-disciplinary drug discovery projects.
Vue d'ensemble
25
25
years of professional experience
7
7
years of post-secondary education
Expérience
Senior Scientist, Structural Biology
NovAlix
Romainville
2023.07 - Actuel
- Production, Purification and Characterization of Recombinant Proteins
- Christallogenesis and Notions of Structural Biology
Senior Scientist Protein Sciences
Galapagos
Romainville
2013.06 - 2023.06
- Production and Purification of Recombinant Proteins
- Biophysics (NanoDSF)
- ADP-glo assay
- Endotoxin Test (LAL)
Scientist Medicinal Chemistry
Galapagos
Romainville
2009.11 - 2013.05
- Design and synthesis of organic molecules for the identification of preclinical candidates in drug discovery
Regulatory Affairs
Merck Sharp & Dhome
Rome (Italy)
2009.07 - 2009.09
Research Chemist, Medicinal Chemistry
Merck Sharp & Dohme
Rome (Italy)
2002.08 - 2009.09
- Design and synthesis of organic molecules for the identification of preclinical candidates in drug discovery
Research Chemist Medicinal Chemist
IRBM
Rome (Italy)
1999.08 - 2002.07
- Design and synthesis of organic molecules for the identification of preclinical candidates in drug discovery
Chemist
CNRS; L. Pasteur University
Strasbourg
1999.02 - 1999.07
Asymmetric Organic Synthesis
Analytical Chemist
IBHI
Rome (Italy)
1998.05 - 1999.01
Analysis of detergents corrosives properties
Formation
Master 2 - Metodologie Farmaceutiche Industriali
Université La Sapienza
Roma 2009.06 - 2009.10
Master - Chemistry
Université "La Spienza"
Rome 1991.09 - 1998.05
Compétences
- Sens des responsabilités
- Relation client
- Rigueur
- Esprit Analitique
Informations complémentaires
- Rental Management of Residential or Commercial Properties
- Health and Saifty and First Aid
- Traveling
Langues
Français
Courant
Italien
Langue maternelle
Anglais
Courant
Espagnol
Notions
Techniques
Protein Sciences
- SDS-PAGE Coomassie
- Western Blot
- NanoDrop
- SEC-MALS
- NanoDSF
- Mosquito
- Akta Pure (simple and bidimentional)
Protein Production in
- Bacteria/Insects/Mammalians
Medicinal Chemistry
- Analytical and Preparative HPLC
- 1H-NMR; 13C-NMR; 19F-NMR
- UPLC-MS
Chronologie
Senior Scientist, Structural Biology
NovAlix
2023.07 - Actuel
Senior Scientist Protein Sciences
Galapagos
2013.06 - 2023.06
Scientist Medicinal Chemistry
Galapagos
2009.11 - 2013.05
Regulatory Affairs
Merck Sharp & Dhome
2009.07 - 2009.09
Master 2 - Metodologie Farmaceutiche Industriali
Université La Sapienza
2009.06 - 2009.10
Research Chemist, Medicinal Chemistry
Merck Sharp & Dohme
2002.08 - 2009.09
Research Chemist Medicinal Chemist
IRBM
1999.08 - 2002.07
Chemist
CNRS; L. Pasteur University
1999.02 - 1999.07
Analytical Chemist
IBHI
1998.05 - 1999.01
Master - Chemistry
Université "La Spienza"
1991.09 - 1998.05