Profil professionnel
Vue d'ensemble
Expérience
Formation
Compétences
Informations complémentaires
Langues
Techniques
Chronologie
Generic
Benedetta Crescenzi

Benedetta Crescenzi

Senior Scientist
Neuilly Plaisance

Profil professionnel

With over 20 years of experience in the pharmaceutical industry, I bring a rare dual expertise in medicinal chemistry and biochemistry/protein sciences. I began my career in a medicinal chemistry group, where I contributed to the discovery of two marketed drugs: raltegravir, an HIV integrase inhibitor, and grazoprevir, an HCV protease inhibitor.


More recently, I joined a protein sciences group, focusing on the production, purification, and characterization of biological targets for drug discovery.
This combined experience—ranging from designing bioactive compounds to mastering biological targets—represents a strong asset for translational research and cross-disciplinary drug discovery projects.

Vue d'ensemble

25
25
years of professional experience
7
7
years of post-secondary education

Expérience

Senior Scientist, Structural Biology

NovAlix
Romainville
07.2023 - Actuel
  • Production, Purification and Characterization of Recombinant Proteins
  • Christallogenesis and Notions of Structural Biology

Senior Scientist Protein Sciences

Galapagos
Romainville
06.2013 - 06.2023
  • Production and Purification of Recombinant Proteins
  • Biophysics (NanoDSF)
  • ADP-glo assay
  • Endotoxin Test (LAL)

Scientist Medicinal Chemistry

Galapagos
Romainville
11.2009 - 05.2013
  • Design and synthesis of organic molecules for the identification of preclinical candidates in drug discovery

Regulatory Affairs

Merck Sharp & Dhome
Rome (Italy)
07.2009 - 09.2009

Research Chemist, Medicinal Chemistry

Merck Sharp & Dohme
Rome (Italy)
08.2002 - 09.2009
  • Design and synthesis of organic molecules for the identification of preclinical candidates in drug discovery

Research Chemist Medicinal Chemist

IRBM
Rome (Italy)
08.1999 - 07.2002
  • Design and synthesis of organic molecules for the identification of preclinical candidates in drug discovery

Chemist

CNRS; L. Pasteur University
Strasbourg
02.1999 - 07.1999

Asymmetric Organic Synthesis

Analytical Chemist

IBHI
Rome (Italy)
05.1998 - 01.1999

Analysis of detergents corrosives properties

Formation

Master 2 - Metodologie Farmaceutiche Industriali

Université La Sapienza
Roma
06.2009 - 10.2009

Master - Chemistry

Université "La Spienza"
Rome
09.1991 - 05.1998

Compétences

  • Sens des responsabilités
  • Relation client
  • Rigueur
  • Esprit Analitique

Informations complémentaires


  • Rental Management of Residential or Commercial Properties
  • Health and Saifty and First Aid
  • Traveling

Langues

Français
Courant
Italien
Langue maternelle
Anglais
Courant
Espagnol
Notions

Techniques

Protein Sciences

  • SDS-PAGE Coomassie
  • Western Blot
  • NanoDrop
  • SEC-MALS
  • NanoDSF
  • Mosquito
  • Akta Pure (simple and bidimentional)


Protein Production in

  • Bacteria/Insects/Mammalians


Medicinal Chemistry

  • Analytical and Preparative HPLC
  • 1H-NMR; 13C-NMR; 19F-NMR
  • UPLC-MS


Chronologie

Senior Scientist, Structural Biology

NovAlix
07.2023 - Actuel

Senior Scientist Protein Sciences

Galapagos
06.2013 - 06.2023

Scientist Medicinal Chemistry

Galapagos
11.2009 - 05.2013

Regulatory Affairs

Merck Sharp & Dhome
07.2009 - 09.2009

Master 2 - Metodologie Farmaceutiche Industriali

Université La Sapienza
06.2009 - 10.2009

Research Chemist, Medicinal Chemistry

Merck Sharp & Dohme
08.2002 - 09.2009

Research Chemist Medicinal Chemist

IRBM
08.1999 - 07.2002

Chemist

CNRS; L. Pasteur University
02.1999 - 07.1999

Analytical Chemist

IBHI
05.1998 - 01.1999

Master - Chemistry

Université "La Spienza"
09.1991 - 05.1998
Benedetta CrescenziSenior Scientist