Yassin Jradi
Biotechnology Engineer (MSc – High Throughput Technologies)
Strasbourg
Summary
Dynamic and results-oriented biotechnology engineer with a Master’s in High Throughput Technologies. Experienced in AAV and protein purification, chromatography techniques (ÄKTA, ion exchange, affinity), and downstream process development through multiple high-impact internships. Skilled in molecular biology, data analysis, and the modeling and simulation of biological systems. Multilingual communicator with a strong scientific mindset and a passion for advancing biotherapeutic innovation.
Overview
2
2
years of professional experience
2
2
years of post-secondary education
4
4
Languages
Work History
AAV Purification Process Development Intern
Max Planck Institute for Infection Biology
Berlin
05.2024 - 08.2024
- Worked within a research team focusing on downstream process development for Adeno-Associated Virus (AAV) vectors.
- Designed and optimized purification workflows for AAVs using affinity chromatography, ion exchange, and TFF (tangential flow filtration).
- Supported the scale-up and robustness testing of AAV purification processes for high-dose gene therapy applications.
- Contributed to the evaluation of next-generation production platforms and their impact on vector purity and yield.
- Collaborated with upstream teams and contributed to documentation and SOPs aligned with GMP-readiness principles.
Protein Purification Intern
Pasteur Institute
Paris
06.2023 - 08.2023
- Designed and implemented a protein purification protocol based on chromatography techniques.
- Prepared and packed chromatography columns, ensuring optimal conditions for downstream separation.
- Operated the ÄKTA system to optimize protein yield and purity, applying key principles of process development.
- Documented all procedures and results according to lab protocols and Good Laboratory Practices (GLP).
Synthetic Biology & Genetic Engineering Intern
Biozentrum – University of Basel
Basel
06.2022 - 08.2022
- Conducted CRISPR-Cas9 genome editing experiments for gene screening and mutation modeling.
- Analyzed gene expression and regulation in bacteria using the lac operon system.
- Performed PCR-RFLP and enzymatic assays to study antibiotic resistance mechanisms.
Education
Engineering Degree - Biotechnology
University of Strasbourg – ESBS
Strasbourg, France 09.2023 - Current
Master of Science - High Throughput Technologies in Biotechnology
University of Strasbourg – ESBS
Strasbourg, France 09.2024 - Current
Skills
Excel & GraphPad Prism Skills
Mathematical Modeling of Biological Systems
Python Programming Expertise
Timeline
Master of Science - High Throughput Technologies in Biotechnology
University of Strasbourg – ESBS
09.2024 - Current
AAV Purification Process Development Intern
Max Planck Institute for Infection Biology
05.2024 - 08.2024
Engineering Degree - Biotechnology
University of Strasbourg – ESBS
09.2023 - Current
Protein Purification Intern
Pasteur Institute
06.2023 - 08.2023
Synthetic Biology & Genetic Engineering Intern
Biozentrum – University of Basel
06.2022 - 08.2022
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