Summary
Overview
Work History
Education
Skills
Publications
Awards
References
Timeline
Generic

Lauri Urvas

PhD Student In Computational Drug Design
Strasbourg,

Summary

The aim of my professional life is to contribute to successful drug discovery projects in the pharmaceutical industry. Currently a PhD student, I have over 3 years of experience in molecular modelling of GPCRs including their receptor-ligand interactions, my main research interest. Experienced also in pharmacology research and organic synthesis, I have a good understanding of the field of drug discovery.

Overview

4
4
years of professional experience
6
6
years of post-secondary education
4
4
Languages

Work History

PhD Student, Laboratory of Therapeutic Innovation

University of Strasbourg
01.2022 - Current
  • Molecular modeling of chemokine receptor dimerization and chemokine receptor - chemokine interactions
  • Structure-based optimization of neuropeptide FF receptor antagonists

Research Assistant, Jyrki Kukkonen Lab

University of Helsinki
01.2021 - 12.2021

Biochemical GPCR research: Running assays in biased signaling, receptor dimerization, and compound screening

Research Assistant, Henri Xhaard Group

University of Helsinki
06.2019 - 12.2020

Using computational tools to research GPCRs and GPCR-ligand interactions. After graduating I participated in teaching related to molecular modelling in drug development

Research Assistant, Jari Yli-kauhaluoma Group

University of Helsinki
05.2018 - 08.2018

Organic synthesis

Research Assistant, Timo Myöhänen Lab

University of Helsinki
06.2017 - 08.2017

Cell culturing, western blotting, assisted in in vivo experiments

Research Assistant, Chemical Microsystems Lab

University of Helsinki
06.2016 - 12.2016

Microchip fabrication and surface functionalization, enzyme immobilization and flow reactor tests

Education

Ph.D. - Pharmacy

University of Strasbourg
France
01.2022 - Current

Master of Science in Pharmacy -

University of Helsinki
Finland
08.2018 - 09.2020

Erasmus Traineeship -

Paris Diderot University
France
Jan 2019 - 05.2019

Bachelor of Science - Pharmacy

University of Helsinki
Finland
08.2015 - 06.2018

Skills

Molecular Dynamics

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Publications

  • Leino TO, Turku A, Urvas L, Adhikari K, Oksanen J, Steynen Y, Yli-Kauhaluoma J, Xhaard H, Kukkonen JP, Wallén EAA. Azulene as a biphenyl mimetic in orexin/hypocretin receptor agonists. Manuscript. 2023


  • Svarcbahs R, Jäntti M, Kilpeläinen T, Julku UH, Urvas L, Kivioja S, Norrbacka S, Myöhänen TT. Prolyl oligopeptidase inhibition activates autophagy via protein phosphatase 2A. Pharmacol Res. 2020;151:104558.


  • Tähkä S, Sarfaz J, Urvas L, Provenzani R, Wiedmer SK, Peltonen J, Jokinen VP, Sikanen TM. Immobilization of proteolytic enzymes on replica-molded thiol-ene micropillar reactors via thiol-gold interaction. Anal Bioanal Chem. 2019;411(11):2339-2349.


  • Kiiski IMA, Pihlaja T, Urvas L, Witos J, Wiedmer SK, Jokinen VP, Sikanen TM. Overcoming the Pitfalls of Cytochrome P450 Immobilization through the Use of Fusogenic Liposomes. Adv Biosyst. 2019;3(1):e1800245.

Awards

  • Poster prize: i-GPCRnet Prize 2022, 2nd international meeting of the IRN i-GPCRnet
  • Award of the Finnish pharmaceutical society for graduating with the highest grades among the Master of Science in Pharmacy graduates from the Faculty of Pharmacy, University of Helsinki in 2020

References

 

Esther Kellenberger

University of Strasbourg, Deputy Dean

+33 3 68 85 42 21

ekellen@unistra.fr


Henri Xhaard

University of Helsinki, Principal Investigator

Mobile: +358 50 448 0878

Email: henri.xhaard@helsinki.fi

Timeline

PhD Student, Laboratory of Therapeutic Innovation

University of Strasbourg
01.2022 - Current

Ph.D. - Pharmacy

University of Strasbourg
01.2022 - Current

Research Assistant, Jyrki Kukkonen Lab

University of Helsinki
01.2021 - 12.2021

Research Assistant, Henri Xhaard Group

University of Helsinki
06.2019 - 12.2020

Master of Science in Pharmacy -

University of Helsinki
08.2018 - 09.2020

Research Assistant, Jari Yli-kauhaluoma Group

University of Helsinki
05.2018 - 08.2018

Research Assistant, Timo Myöhänen Lab

University of Helsinki
06.2017 - 08.2017

Research Assistant, Chemical Microsystems Lab

University of Helsinki
06.2016 - 12.2016

Bachelor of Science - Pharmacy

University of Helsinki
08.2015 - 06.2018

Erasmus Traineeship -

Paris Diderot University
Jan 2019 - 05.2019
Lauri UrvasPhD Student In Computational Drug Design