Summary
Overview
Work History
Education
Skills
Languages
Training
Hobbies and Interests
Timeline
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Dihia Akkacha

Dihia Akkacha

PHARMACEUTICAL DEVELOPMENT AND PROCESS OPTIMIZATION PROJECT LEAD
DREUX,France

Summary

I'm fueled by turning ideas into real products, from concept to completion. I find joy in developing formulations, navigating regulations, and ensuring projects hit their marks. With three years as Pharmaceutical Development and Process Optimization project Lead, I am equipped with a strong understanding of drug development processes and a proven track record of successfully leading projects to completion. Committed to delivering high-quality results, I am eager to utilize my skills and expertise to contribute to the success of an organization in the pharmaceutical sector.

Overview

3
3
years of professional experience

Work History

PHARMACEUTICAL DEVELOPMENT AND INDUSTRIAL TRANSFER PROJECT LEAD

MAYOLY Consumer Healthcare
01.2022 - Current
  • Led four oral dosage form projects, overseeing formulation design, process development, and scale-up. Ensured timely delivery of high-quality pharmaceutical products.
  • Collaborated with external partners for efficient technological transfer of two drug products.
  • Developed a new formulation for an oral dosage form using Design of Experiments (DOE), optimizing parameters for enhanced product quality and efficiency.
  • Conducted rigorous statistical analysis using JMP software for both industrial and validation scale batches, providing crucial insights for process optimization.
  • Delivered monthly formulation-related presentations to the development industrialization department, enhancing communication and knowledge transfer within the organization.
  • Provided invaluable support to the analytical team by consolidating results and seamlessly integrating them into development reports, ensuring data integrity and facilitating project progression.
  • Reported regularly to managers on project progress and technical problems.
  • Evaluated the feasibility of four eco-responsible packaging alternatives, conducting laboratory-scale tests on recyclable materials while monitoring stability, leading to the successful implementation of the most suitable packaging solution.
  • Provided crucial support to the regulatory department, ensuring timely submission of two registration dossiers while maintaining compliance with regulatory requirements and meeting deadlines.
  • Implemented comprehensive strategies for blend homogeneity evaluation, uniformity of dosage forms, and holding time validation for solid dosage forms, aligning with regulatory guidelines and industry best practices.
  • Managed the formulation laboratory, streamlining material management, equipment maintenance, and SOP creation to ensure a well-functioning and compliant laboratory environment.

Formulation Scientist

IPSEN CONSUMER HEALTHCARE
02.2021 - 10.2021
  • Liaised with industrial team to support all facets related to manufacturing of scale-up and validation batches for a project of solid dosage form
  • Utilized statistical tools to evaluate data and provide insights for decision-making
  • Maintained effective communication with senior stakeholders to keep them informed of project technical progress
  • Conducted bibliographic research to inform project decisions
  • Successfully scaled up process from laboratory scale to industrial by delivering outstanding technical services, writing protocols and reports
  • Conducted lab-scale manufacturing of suspensions, while managing materials and writing study protocols and reports.
  • Improved drug formulation quality by developing and optimizing pharmaceutical materials.
  • Enhanced product stability through thorough evaluation and testing of various excipients.
  • Collaborated with cross-functional teams to establish robust manufacturing processes for new products.
  • Developed innovative drug delivery systems for enhanced patient compliance and therapeutic effectiveness.

ANALYTICAL CHEMISTRY TECHNICIAN

LABORATORY OF ANALYTICAL CHEMISTRY, UNIVERSITY MOULOUD MAMMERI
01.2018 - 06.2018
  • Conducted pivotal tests on oral dosage forms, including dissolution, disintegration time, and UV assay, gaining proficiency in sample preparation and quantitative analysis of active pharmaceutical ingredients
  • Developed analytical protocols and reports for stability studies, building foundational skills for pharmaceutical analysis under mentorship.

Education

Master’s Degree - Pharmaceutical industry formulation development

Lille, France

PhD in Pharmacy -

Tizi ouzou, Algeria

Skills

  • Expertise in formulating oral dosage forms, semi-liquid formulations, and suspensions
  • Quality by Design (QbD) methodologies
  • Statistical analysis (JMP software, Minitab, Excel)
  • QBD documentation (QTPP, risk assessment, gap analysis)
  • Regulatory compliance (GMP, FDA, EMA)
  • Bibliographic research and analysis
  • Project management and documentation
  • Effective communication and presentation skill
  • Project management and documentation
  • Effective communication and presentation skill

Languages

English: Advanced
French, Tamazight, Arabic: Fluent

Training

  • JMP and Minitab Statistical Software and statistical training with Soladis: Expertise in statistical analysis and data visualisation.
  • Quality Management: Kaizen and A3: proficiency in continuous improvement and problem-solving techniques.
  • Process Improvement: 5 Axes Business Excellence
  • Tablet coating: Depth knowledge and practical skills in coating processes within the pharmaceutical industry.
  • ICHQ3D guidelines: understanding of regulatory requirements for elemental impurities in pharmaceutical products.
  • Clinical Trials Leadership Training | Paris Diderot University, Faculty of Medicine, France.

Hobbies and Interests

  • Creative Communication: Craft visually impactful PowerPoint presentations, merging creativity and design to effectively communicate information.
  • Active Lifestyle: Enjoy an active lifestyle by playing frisbee, fostering physical activity and social connections
  • Nature Exploration: Cultivate a passion for exploring local trails and nature reserves through hiking, appreciating the tranquility and beauty of the outdoors.
  • Linguistic Diversity: Intrigued by linguistic diversity, I am fluent in Arabic, French, and English. Currently committed to mastering Spanish to broaden cultural horizons and enhance communication skills.

Timeline

PHARMACEUTICAL DEVELOPMENT AND INDUSTRIAL TRANSFER PROJECT LEAD

MAYOLY Consumer Healthcare
01.2022 - Current

Formulation Scientist

IPSEN CONSUMER HEALTHCARE
02.2021 - 10.2021

ANALYTICAL CHEMISTRY TECHNICIAN

LABORATORY OF ANALYTICAL CHEMISTRY, UNIVERSITY MOULOUD MAMMERI
01.2018 - 06.2018

Master’s Degree - Pharmaceutical industry formulation development

Lille, France

PhD in Pharmacy -

Tizi ouzou, Algeria
Dihia AkkachaPHARMACEUTICAL DEVELOPMENT AND PROCESS OPTIMIZATION PROJECT LEAD